This invention provides a system and method for fusing and synthesizing a plurality of medical images defined by a plurality of imaging parameters allowing visual enhancements of each image data set to be combined. The system provides an image fusion process/processor that fuses a plurality of magnetic resonance imaging datasets. A first image dataset of the datasets is defined by apparent diffusion coefficient (ADC) values. A second image dataset of the MRI datasets is defined by at least one parameter other than the ADC values. The image fusion processor generates a fused response image that visually displays a combination of image features generated by the ADC values combined with image features generated by the at least one parameter other than the ADC values. The fused response image can illustratively include at least one of color-enhanced regions of interest and intensity-enhanced regions of interest.