PROCÉDÉS DE RÉALISATION DE CONSTRUCTIONS MÉDICALES DE FIBRE DE COLLAGÈNE ET DE CONSTRUCTIONS MÉDICALES AFFÉRENTES, Y COMPRIS DE GUIDES NERVEUX ET DE TIMBRES TRANSDERMIQUES
Methods for making collagen based biocomposite constructs and related devices include: (a) winding at least one collagen fiber a number of revolutions about a length of a support member having a long axis, the winding having at least one defined pitch and/or fiber angle relative to the long axis of the support member to form an elongate construct； and (b) applying a fluid polymeric material, such as, for example, an acrylate emulsion and/or other thermoplastic material, onto the collagen fiber during the winding step. Optionally, the fluid polymeric material can include antibiotics and/or other therapeutic agents for additional function/utility.
