Venous compression in the neck reduced the extent of axonal injury in astandardized mild TBImodel in rodents. The mechanism restricted brain venous drainage and increasedthe centralnervous system blood volume and pressure, thus shifting intracranialphysiology to the steep partof the volume-compliance curve. The lack of compliance inside the confines ofthe skull andspinal canal prevented slosh energy absorption and the resultant axonal injuryby causing them toapproach a more elastic collision when the skull was struck during the weightdrop method. Afirst embodiment can be a device comprising a means to reduce SLOSH energyabsorption in afluid containing organism by reducing the flow of one or more outflow vesselsof the cranium bycompressing said vessels.
