An itching water applicable to postoperative wound itching and a process for the production of it are provived. The itching water comprising Lignum Aquilariae Resinatum, Radix Notoginseng, Cornus Officinalis, Fructus Gardenia, Radix Flemingiae, Myrrh, Fructus Chaenomelis, Radix Scutellariae, Rhizoma Alismatis, Zanthoxylum Pipertum DC, Salvia Miltiorrhiza, Radix Angelicae Sinensis, Rheum Palmatum, Angelica Dahurica, Acorus tatarinowii, Radix Paeoniae Rubra, Lignum Sappan, Cinnamomum Cassia Presl, Radix Sanguisorbae, Asarum Sieboldii, Rhizoma Atractylodis, Pinellia Ternate, Common Clubmoss Herb, Pyritum, Radix Curcumae Aromaticae, Radix Saposhnikoviae, Rhizoma et Radix Notopterygii, Cortex Moutan, Boswellia Carteri, Radix Linderae and medical ethanol. The itching water of the invention has reasonable composition, less dosage, environment protection, simple operation, remarkable therapeutic effect and less side effects.