GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
DING, XIAO,丁晓,丁曉,HO, MING HSUN,何明勳,何明勳,REN, FENG,任峰,任峰,YU, HAIHUA,余海华,余海華,ZHAN, YANG,湛洋,湛洋
申请号：
TW107124022
公开号：
TW201920197A
申请日:
2018.07.12
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
The present invention relates to novel compounds that inhibit LRRK2 kinase activity, to processes for their preparation, to compositions containing them and to their use in the treatment of or prevention of diseases associated with or characterized by LRRK2 kinase activity, for example Parkinson’s disease, Alzheimer’s disease and amyotrophic lateral sclerosis(ALS).本發明係關於抑制LRRK2激酶活性之新穎化合物、其製備方法、包含彼等之組成物及其於治療或防止與LRRK2激酶活性有關或以其為特徵之疾病的用途，例如帕金森氏症、阿茲海默症和肌萎縮性脊髓側索硬化症(ALS)。
