MADISON, EDWIN L.,NGUYEN, JACK,RUGGLES, SANDRA WAUGH,THANOS, CHRISTOPHER D.
申请号:
CA2626356
公开号:
CA2626356C
申请日:
2006.10.20
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Provided are methods for and compounds for modulating the complement system.In particular, compounds are provided that inhibit complement activation andcompounds are provided that promote complement activation. The compounds aretherapeutics by virtue of their effects on the complement system. Hence, thecompounds that inhibit complement activation can be used for treatment ofischemic and reperfusion disorders, including myocardial infarction andstroke, sepsis, autoimmune diseases, inflammatory diseases and diseases withan inflammatory component, including Alzheimer's Disease and otherneurodegenerative disorder.