This invention, meteor phosphorus being something regarding the blood vessel new life inhibiter which includes as the active ingredient, in detail, at embryo bud latter-term stage and the raw latter part floor of mouse occurrence being revealed high-level in the star condition cell of the brain and the retina, being detected from the star condition cell ended feet which are surrounded with the especially blood vessel, promoting the revelation of the toronbosuponjin 1/ 2 (TSP 1/ 2) via the self secretion, controlling the blood vessel new life, includes the meteor phosphorus which makes the maturity of the blood vessel promote as the active ingredient it is something regarding the blood vessel new life inhibiter. As for the meteor phosphorus of this invention, by the fact that the blood vessel new life is controlled it can use for the usefulness in the pharmacy composition for blood vessel-related diseased prevention and the health food for blood vessel-related diseased prevention.本発明は、メテオリンを有効成分として含む血管新生抑制剤に関するもので、詳細には、マウス発生の胚芽後期段階と生後段階で脳と網膜の星状細胞に高度に発現されて、特に血管で取り囲まれた星状細胞エンドフィートから検出されて、自己分泌を通じてトロンボスポンジン-1/-2(TSP-1/-2)の発現を促進して血管新生を抑制して、血管の成熟を促進させるメテオリンを有効成分として含む、血管新生抑制剤に関するものである。本発明のメテオリンは、血管新生を抑制することで血管関連疾患予防用薬学的組成物および血管関連疾患予防用健康食品に有用に使用することができる。
