A portable ultrafine nebulizer comprises a housing, an atomizing nozzle located at the front port of the housing, an air turbine deposited inside the housing, an air flow guide device fixed at the front port of the housing, and a water pump for pumping liquid; the air flow guide device is provided with a plurality of air flow guide blades distributed uniformly around the periphery of the atomizing nozzle, and each of the air flow guide blades is provided with a guide surface; in the atomizing nozzle is provided with a spiral channel and a fluid channel communicated with the water pump, the atomizing nozzle is provided with a spray port at the front end, and the spray port is communicated with the fluid channel through the spiral channel; the air turbine, the air flow guide blades and the spray port are distributed successively along the airflow direction.