Paul W Behrens,John M Thompson,Kirk Apt,Joseph W. Pfeifer, III,James P Wynn,James Casey Lippmeier,Jaouad Fichtali,Jon Hansen
申请号：
US14975670
公开号：
US09834799B2
申请日:
2015.12.18
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Methods for production of highly unsaturated fatty acids by marine microorganisms, including the heterotrophic marine dinoflagellate Crypthecodinium, using low levels of chloride ion are disclosed. Specifically, methods of increasing production of highly unsaturated fatty acids by marine microorganisms while growing in low chloride media by manipulating sodium ion and potassium ion levels. The invention also relates to methods of production of highly unsaturated fatty acids by marine organisms at low pH levels, and includes methods for generation of low pH tolerant strains.
