An angioplasty device for insertion into an artery having undesired deposits includes a guide wire for insertion into the artery an elongated flexible catheter for insertion into the artery over the guide wire, the catheter having a proximal end, a distal end, and one or more lumens extending longitudinally therethrough an energizable ultrasonic transducer inside the distal end of the guide wire an inflatable balloon overlying the catheter and the transducer such that when the transducer is energized, energy from the transducer is transmitted through the balloon to the deposits.
