MITCHELL, SCOTT A.,CURRIE, KEVIN S.,BLOMGREN, PETER A.,KROPF, JEFFREY E.,LEE, SEUNG H.,XU, JIANJUN,STAFFORD, DOUGLAS G.
申请号:
CA2745871
公开号:
CA2745871C
申请日:
2009.12.07
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Certain imidazopyrazines and pharmaceutical compositions thereof are providedherein. Methods of treatingpa-tients suffering from certain diseases and disorders responsive to theinhibition of Syk activity, which comprises administering tosuch patients an amount of at least one chemical entity effective to reducesigns or symptoms of the disease or disorder areprovid-ed. Also provided are methods for determining the presence or absenceof Syk kinase in a sample.