BEDI Atul;RAVI Rajani;THE JOHNS HOPKINS UNIVERSITY
发明人:
BEDI Atul,RAVI Rajani
申请号：
IL27090119
公开号：
IL270901D0
申请日:
2019.11.25
申请国别(地区):
IL
年份:
2020
代理人:
摘要：
The invention provides multifunctional antibody-ligand traps and methods of using them to counteract immune tolerance and/or immune dysfunction. The multifunctional antibody-ligand traps and fusion proteins of the invention can counteract immune dysfunction in order to restore and unleash antitumor or pathogen-directed immune responses. Provided here are promising immunotherapeutic agents for treatment and prevention of cancers, infectious diseases, and immuno-inflammatory disorders.
