A system and method for determining a pattern of activation of a heart of a subject. An imaging dataset is acquired of a portion of the subject including the heart and the imaging dataset is processed=to identify a motion parameter of the heart. The motion parameter of the heart is mapped over time to create a pattern of activation of the heart. A global LV dyssynchrony index is automatically generated and analyzed using changes in wall thickness of the heart over time. A report is generated indicating the pattern of activation of the heart of the subject.
