您的位置: 首页 > 农业专利 > 详情页

Self-assembled peptide nanostructures by exploiting conformational change, biosensor using the same and detection method of biomolecules using the same
专利权人:
发明人:
Yong-beom Lim,So-hee Han
申请号:
US14712184
公开号:
US09732120B2
申请日:
2015.05.14
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure relates to a self-assembled peptide nanostructure including at least one amphiphilic peptide and a biosensor using the same. The amphiphilic peptide is a hairpin-shaped amphiphilic peptide including a hydrophilic domain having an α-helical structure and a hydrophobic domain. The N-terminal of the hydrophobic domain is a pyrene group. Since the self-assembled peptide nanostructure is derived from an RNA, DNA or amino acid sequence capable of recognizing a specific target substance, it does not recognize other substances but exhibits high selectivity for the target substance. Specifically, since the self-assembled peptide nanostructure has an excimer fluorescence peak at 480 nm through binding with the target substance, it can be usefully used in medical applications such as diagnosis of diseases.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充