Quinazoline derivatives for the treatment of viral infections and further diseases

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专利权人:

JANSSEN R&D IRELAND

发明人:

RABOISSON PIERRE JEAN-MARIE BERNARD,MC GOWAN DAVID,EMBRECHTS WERNER,JONCKERS TIM HUGO MARIA,LAST STEFAAN JULIEN,PIETERS SERGE MARIA ALOYSIUS

申请号：

NZ61664212

公开号：

NZ616642A

申请日:

2012.05.18

申请国别(地区):

NZ

年份:

2015

代理人:

摘要：

This disclosure relates to 2,4-aminoquinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use in therapy of disorders in which the modulation of toll - like - receptors is involved, typically in the treatment of viral infections. compounds of the disclosure include: (3S)-3-[(2-amino-5-methylquinazolin-4-yl)amino]hexan-1-ol, (3S)-3-[(2-amino-6,7-dimethoxyquinazolin-4-yl)amino]hexan-1-ol, and (3S)-3-[(2-amino-8-fluoroquinazolin-4-yl)amino]hexan-1-ol

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/