UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
发明人:
MOURADIAN, M., MARAL,BRAITHWAITE, STEVEN,VORONKOV, MICHAEL
申请号:
EP12777826
公开号:
EP2701707A4
申请日:
2012.04.26
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Methods of treating patients with dyskinesias, by administering a therapeutically effective amount of a dual-action mu-opioid receptor antagonist/kappa-opioid receptor agonist or prodrug thereof to a subject in need thereof, sufficient to mitigate the dyskinesia. Alternatively, a combination of both a mu-opioid receptor antagonist or prodrug thereof, and a kappa-opioid receptor agonist or prodrug thereof can be administered, either together or separately.