THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY
发明人:
PASINI, DAMIANO,KHANOKI, SAJAD ARABNEJAD,TANZER, MICHAEL
申请号：
EP12859682
公开号：
EP2793756A4
申请日:
2012.12.21
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
An implant for bone replacement comprises a graded cellular body having a non-homogeneous distribution of material properties. The graded cellular body is defined by a plurality of unit cells, each of said unit cells having a lattice microstructure and a cell topology, either closed or open, and a pore geometry. The pore geometry is defined by pore size, pore shape and wall thickness. The pore size of the unit cells at implant boundaries is in the range between 50 micron and 800 micron to ease bone ingrowth, and said cell topology is optimized to ease mass transport conditions that influence cell phenotype, tissue ingrowth, and nutrient settings. The lattice microstructure has a predetermined density pattern in said implant to minimize bone loss and interface failure when implanted. The lattice microstructure defines a porosity of greater than 40%.
