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二量体化合物およびニューラミニダーゼ阻害剤として
专利权人:
バイオタ、サイアンティフィック、マネージメント、プロプライエタリ、リミテッド
发明人:
ウェン‐ヤン、ウー,ジン、ベティ
申请号:
JP2000605578
公开号:
JP5160000B2
申请日:
2000.03.09
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
This invention relates to novel dimeric compounds, methods for their preparation, pharmaceutical formulations thereof, and their use as antiviral agents. The compounds are particularly useful against influenza virus. In particular the invention provides a dimeric compound which comprises two neuraminidase binding groups attached to a spacer or linking group. Preferably the dimeric molecule comprises two neuraminidase-binding neuraminic acid (sialic acid) or cyclopentyl or cyclohexenyl carboxylic acid derivatives covalently attached to a common spacer group. Pharmaceutical compositions and methods of treatment, prophylaxis and diagnosis are disclosed and claimed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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