PROBLEM TO BE SOLVED: To provide a novel medicine for prevention and/or treatment of ophthalmologic disease caused by ocular neovascularization.SOLUTION: The present invention provides a medicine for prevention and/or treatment of ophthalmologic disease caused by ocular neovascularization, the medicine containing, as an active ingredient, a pyrazolone derivative such as 3-methyl-1-phenyl-2-pyrazoline-5-one or a physiologically acceptable salt thereof, or a hydrate or a solvate thereof.SELECTED DRAWING: None【課題】眼血管新生に起因する眼科疾患の予防及び/又は治療のための新規な医薬を提供すること。【解決手段】3-メチル-1-フェニル-2-ピラゾリン-5-オンなどのピラゾロン誘導体若しくはその生理的に許容される塩、又はそれらの水和物若しくは溶媒和物を有効成分として含有する、眼血管新生に起因する眼科疾患の予防及び/又は治療のための医薬。【選択図】なし