PROBLEM TO BE SOLVED: To provide an antigen-binding molecule for reducing an antigen concentration in plasma.SOLUTION: The present invention provides an antigen-binding molecule that promotes the elimination of, from blood, an antigen having two or more bioactivities, which are difficult to inhibit only with a single antigen-binding molecule, thus reducing the bioactivities. The present invention further provides a method for producing the antigen-binding molecule, and a pharmaceutical composition containing the molecule as an active ingredient.SELECTED DRAWING: None【課題】血漿中の抗原濃度を低下させる抗原結合分子の提供。【解決手段】一種類の抗原結合分子のみで生理活性の阻害が困難な，２種以上の生理活性を有する抗原に対し，血中からの消失を捉進する事で，その生理活性を低減させる事が可能な抗原結合分子を提供。更に該抗原結合分子の製造方法，及び当該分子を有効成分とする医薬組成物を提供。【選択図】なし
