THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人:
LI, Shaowei,HU, Min,LORENZ, Hermann Peter
申请号：
WO2018US25846
公开号：
WO2018187298(A1)
申请日:
2018.04.03
申请国别(地区):
世界知识产权组织国际局
年份:
2018
代理人:
摘要：
Certain relatively small cells present in the periphery blood of mammals can be activated to form pluripotent stem cell populations. These small cells are generally less than five micrometers in diameter and are CD45-positive, and are referred to herein as CD45+ cells or dormant tiny cells. Accordingly, provided are cell populations and compositions with enriched dormant tiny cells from blood samples and methods and compositions for activating these dormant tiny cells. Upon differentiation, the activated stem cells can be used for various therapeutic purposes.
