TETRAHYDRO-BENZO[D]AZEPINE DERIVATIVES AS GPR120 MODULATORS

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专利权人:

CALDAN THERAPEUTICS LIMITED

发明人:

Jane BROWN,Stephen CONNOLLY,Steffen V.F. HANSEN,Gavin MILNE,Bharat SHIMPUKADE,Don SMYTH,Gerard THOMAS,Trond ULVEN,Matjaz BRVAR,Aaron RIGBY

申请号：

US16496786

公开号：

US20200317619A1

申请日:

2018.03.26

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Novel tetrahydroisoquinoline and tetrahydrobenzazepine compounds of formula (I) capable of modulating the G-protein-coupled receptor GPR120, compositions comprising the compounds, and methods for their use for controlling insulin levels in vivo and for the treatment of conditions such as of diabetes, inflammation, obesity and metabolic diseases. (I)

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