Van Ommen, Garrit-Jan Boudewijn,Aartsma-Rus, Annemieke,Van Deutekom, Judith Christina Theodora,De Kimpe, Josephus Johannes,Verbeek, Joseph Stephan,Yilmaz-Elis, Aliye Seda
申请号：
AU2010335039
公开号：
AU2010335039A2
申请日:
2010.12.22
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The invention provides two types of oligonucleotides for treating an inflammatory disorder: an oligonucleotide which is able of altering the splicing of a pre-mRNA encoding a C5 in order to decrease the amount of a C5a and an oligonucleotide which is able of altering the splicing of a pre-mRNA encoding a IL-1RAcP in order to increase the amount of a soluble IL-1RAcP.Theinvention further provides the use of said oligonucleotides for preventing or treating an inflammatory disorder.
