Geofrey De Visscher,Walter Eevers,Nicolas Schüwer,Takayuki Shigematsu,Mayu Takeiri,Jeffrey A. Hubbell,Federico Tortelli,De Titta Alexandre,Sandra Amiguet Vercher
申请号：
US14912767
公开号：
US20160199343A1
申请日:
2014.08.25
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to the treatment of wounds. More particularly, it relates to compounds according to Formula (1) for use in methods of promoting wound healing, to formulations which incorporate these compounds and to a method of treating wounds using such compounds and formulations: wherein R1 and R2 may be the same or different and are selected from the group consisting of hydrogen (H) and a physiologically hydrolysable chemical group consisting of alkyl, alkyl carbonyl, alkenylcarbonyl arylcarbonyl, heteroarylcarbonyl, alkoxycarbonyl, aryloxycarbonyl, heteroaryloxycarbonyl, alkylether, alkenylether, arylether, and heteroarylether groups wherein the alkyl group or moiety consists of unsubstituted or substituted, straight-chain or branched-chain and cyclic alkyl groups having 2-22 carbon atoms, wherein the alkenyl moiety consists of unsubstituted and substituted, straight-chain or branched-chain and cyclic alkenyl groups having 2-22 carbon atoms, wherein the aryl moiety consists of unsubstituted and substituted phenyl, and phenalkyl groups wherein the alkyl moiety contains 1-3 carbon atoms and the phenyl moiety is unsubstituted or substituted, and the heteroaryl moiety is an aromatic 5- or 6-membered heterocyclic ring containing one or two heteroatoms selected from the group consisting of nitrogen, oxygen, and sulphur.
