Provided herein is a scaffold comprising a decellularized meniscus tissue, wherein the scaffold is covalently conjugated with heparin and a growth factor. Also provided herein is a method of repairing and/or treating a tissue injury in a subject in need thereof, comprising: providing a scaffold comprising a decellularized meniscus tissue； and repairing and/or treating the tissue injury by implanting the scaffold over the tear, wherein the scaffold is covalently conjugated with heparin and a growth factor.
