Antonio Lanzavecchia,Joshua Tan,Abdi Abdirahman,Kathrin Pieper,Luca Piccoli,Peter Charles Bull
申请号:
US15738912
公开号:
US20180179274A1
申请日:
2016.06.24
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides a protein comprising a mutated LAIR-1 fragment, which broadly binds to erythrocytes infected with Plasmodium falciparum. The protein comprising the mutated LAIR-1 fragment may be useful in the prevention and/or treatment of malaria. The present invention furthermore provides a nucleic acid encoding a mutated LAIR-1 fragment, a vector comprising such a nucleic acid as well as a respective pharmaceutical composition.