CALITOR SCIENCES, LLC;SUNSHINE LAKE PHARMA CO., LTD.
发明人:
Ning Xi,Yanjun WU
申请号：
US15300284
公开号：
US20170183358A1
申请日:
2015.04.16
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides substituted bicyclic pyrazolone compounds, which are used to inhibit or modulate the activity of receptor tyrosine kinases, especially Axl, Mer, c-Met and Ron. The invention also provides pharmaceutical compositions comprising the compound disclosed herein, and a method of preventing, treating or lessening the severity of a proliferative disorder in a patient with the compounds or the pharmaceutical compositions disclosed herein.
