An expansion and compression instrument for fracture fixation includes a first handle member, a second handle member, a bearing assembly, and a replaceable tip insert. The bearing assembly axially receives a driver. The replaceable tip insert is adapted to engage an aperture of a fracture fixation plate. The driver is adapted to engage the head of a bone screw, partially threaded into bone proximate the fracture and disposed through a longitudinal slot of the plate. Manual manipulation of the handle members together or apart causes the driver head and replaceable tip insert to become farther apart or closer together, respectively. Pivotal or hinged attachment of the bearing assembly to a handle member permits pivotal movement of the driver relative to the handle member and permits the jaws of the replaceable tip insert to remain in substantial engagement with the fracture fixation plate during expansion and compression.