LIPOSOME CONTAINING SHRNA MOLECULE FOR THYMIDYLATE SYNTHASE, AND USE FOR SAME

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专利权人:

发明人:

申请号：

HK14103539.6

公开号：

HK1190325A

申请日:

2014.04.14

申请国别(地区):

HK

年份:

2014

代理人:

摘要：

This method provides a method for delivering shRNA targeting TS in vivo. In addition, the following is provided: an antitumor agent, which comprises short hairpin RNA (shRNA) capable of inhibiting expression of thymidylate synthase by RNAi action and a PEG-modified cationic liposome, wherein the shRNA is bound to the surface of the PEG-modified cationic liposome and has an overhang comprising at least two nucleotides at the 3 end.

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中国工程科技知识中心

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http://www.ckcest.cn/home/