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New condensed aminodihydrotiazine derivative
专利权人:
EISAI R&D MANAGEMENT CO.; LTD.
发明人:
MOTOKI, TAKAFUMI,TAKEDA, KUNITOSHI,KITA, YOICHI,TAKAISHI, MAMORU,SUZUKI, YUICHI,ISHIDA, TASUKU
申请号:
ES09817719
公开号:
ES2539859T3
申请日:
2009.09.28
申请国别(地区):
ES
年份:
2015
代理人:
摘要:
A compound represented by the formula (I): ** Formula ** or a pharmaceutically acceptable salt thereof, or a solvate thereof, wherein Ring A 5 is a C6-14 aryl group that may have 1 to 3 substituents selected from the Substituent Group α, a 5- to 6-membered heteroaryl group that may have 1 to 3 substituents selected from the Substituent Group α or a benzo-condensed heterocyclic group of 9 to 10 members that may have 1 to 3 substituents selected from the Substituent Group α, L is a single bond, an oxygen atom, -NRLCO- (in which RL is a hydrogen atom or a C1-6 alkyl group that may have 1 to 3 substituents selected from the Substituent Group α), a group -NRLC C1-6alkyl (in which RL is a hydrogen atom or a C1-6 alkyl group that may have 1 to 3 substituents selected from Substituent Group α), -NRLSO2- (in which RL is an atom of hydrogen or a C1-6 alkyl group that may have 1 to 3 substitutes sources selected from Substituent Group α), a C1-6 alkylene group that may have 1 to 3 substituents selected from Substituent Group α, a C2-6 alkenyl group that may have 1 to 3 substituents selected from Substituent Group α, or a C2-6 alkynylene group which may have 1 to 3 substituents selected from Substituent Group α, Ring B is a C3-8 cycloalkyl group which may have 1 to 3 substituents selected from Substituent Group α, an aryl group of C6-14 which may have 1 to 3 substituents selected from the Substituent Group α, or a 5-10 membered heterocyclic group that may have 1 to 3 substituents selected from the Substituent Group α, X is a single bond or a C1-3 alkylene group which may having 1 to 3 substituents selected from the Substituent Group α, Y is a C1-3 alkylene group which may have 1 to 3 substituents selected from the Substituent Group α or a C2-3 alkenylene group which may have 1 to 3 Substituents selected from Substituent Group α, Z is an oxygen atom, a sulfur atom, a sulfoxide, a sulfone or -NRM- (in which RM is a hydrogen atom, a C1-6 alkyl group which may have 1 to 3 substitue
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