ЧЭНЬ Си (US),ФАН Пинчэнь (US),ЛИ Яньдун (US),ПАУЭРС Джей П. (US),МАЛАТОНГ Виенгкхам (US),ПУННА Сринивас (US),ТАНАКА Хироко (US),ЧЖАН Пэнли (US),ДРАГОЛИ Дин (US)
申请号：
RU2015127027
公开号：
RU2015127027A
申请日:
2013.12.06
申请国别(地区):
RU
年份:
2017
代理人:
摘要：
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.
