Patricia Andres;Hugh Y. Rienhoff, Jr.;Amy E. Tapper;Stephan D. Parent;Jason A. Hanko;Huamin Zhang
发明人:
Amy E. Tapper,Hugh Y. Rienhoff, Jr.,Stephan D. Parent,Patricia Andres,Jason A. Hanko,Huamin Zhang
申请号:
US13198287
公开号:
US08710087B2
申请日:
2011.08.04
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.