The present application relates to a pharmaceutical composition comprising attenuated pneumococcal strains and uses thereof for preventing or treating allergic diseases. A pneumococcal pep27 mutant strain according to the present invention is sufficiently attenuated, thereby having an advantage of securing safeness during throat infection, intraperitoneal injection, and blood injection.COPYRIGHT KIPO 2020본원은 약독화된 폐렴구균 균주를 포함하는 약제학적 조성물, 및 이의 알레르기성 질환의 예방 또는 치료를 위한 용도에 관한 것이다.