The present invention relates to compounds of formula Iwherein Y is N or C-R1'； R1' is hydrogen or F； R1 is hydrogen, halogen or lower alkyl substituted by halogen； R2 is hydrogen or lower alkyl； or R2 forms together with R4 a 6-membered heterocyclic ring containing -CH2-CH2-O-CH2- or -CH2-CH2-NR-C(O)-； R is hydrogen, lower alkyl, phenyl or benzyl； R3 is phenyl or pyridinyl, wherein the N atom in the pyridinyl group may be in different positions； R4' is hydrogen, lower alkyl or lower alkoxyalkyl； R4 is hydrogen, lower alkyl, phenyl optionally substituted by halogen or lower alkoxy, or is cycloalkyl, or is pyridinyl optionally substituted by halogen, lower alkyl, lower alkoxy or =O, or is pyrimidinyl optionally substituted by lower alkyl, lower alkoxy or =O, or is 1-lower alkyl-pyridinyl, or is pyrazinyl, or is pyridazinyl optionally substituted by lower alkyl, lower alkoxy or =O, or is 1-methylpyrrolo[2,3-b]pyridine-5-yl, or is 6-imidazo[1,2-b]pyridazin-6-yl； or R4 forms together with R4' a 4-, 5- or 6-membered heterocyclic ring containing -(CH2)5-, -CH2-CH2-O-CH2-CH2-, CH2-CH2-CH2-, CH2-CH2-CH2-CH2-, CH2-O-CH2-CH2-CH2- or CH2-CH2-CH2-O-CH2-； R5 and R5' are hydrogen or lower alkyl； or R4 forms together with R5 a saturated 5-membered ring containing -CH2-CH2-CH2-； or to pharmaceutically acceptable salts or acid addition salts, racemic mixtures thereof, or to corresponding enantiomers and/or optical isomers and/or stereoisomers thereof. Said compounds may be used for the treatment of Parkinson's disease, anxiety, emesis, obsessive compulsive disorder, autism, neuroprotection, cancer, depression and diabetes type 2.Изобретение относится к соединениям формулы Iгде Y представляет собой N или C-R1'； R1' представляет собой водород или F； R1 представляет собой водород, галоген или низший алкил, замещенный галогеном； R2 представляет собой водород или низший алкил； или R2 образует вместе с R4 6-членное гетероциклическое кольцо, содержащее -CH2-CH2-O-CH2- или -CH2-CH2-NR-C(O)-
