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Methods and systems of detecting exocytosis of a target molecule from a population of cells
专利权人:
发明人:
Mark Alan Messerli,Emma Heart,Munan Xu,Shanta Menon Messerli
申请号:
US14889568
公开号:
US09739734B2
申请日:
2014.05.12
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A method of detecting exocytosis of a target molecule from a population of cells derived from a human subject, includes applying first and second electrical signals, each having a respective frequency, across the population of cells. Each of the first and second electrical signals being either an alternating current or an alternating voltage. The method includes measuring a first voltage change if the first electrical signal is an alternating current or measuring a first current change if the first electrical signal is an alternating voltage, and measuring a second voltage change if the second electrical signal is an alternating current or measuring a second current change if the second electrical signal is an alternating voltage. The method includes determining an electrical impedance of the population of cells, a change in that impedance indicating an amount of the target molecule released from the population of cells.
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