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NOUVEAU PEPTIDE ANTIGÈNE CONTRE LE CANCER ET APPLICATIONS
专利权人:
TORAY INDUSTRIES; INC.
发明人:
申请号:
EP05814555.8
公开号:
EP1835027B1
申请日:
2005.12.06
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Novel peptides useful as a therapeutic and/or prophylactic agent of cancers, as well as medical uses thereof, are described. Each of these peptides have a consecutive amino acid sequence within a specific region of YKL-40 antigen expressing on the cell surface of brain tumor cells, that is, within the region aa10-19, aa49-61, aa74-83, aa96-117, aa152-161, aa177-185, aa202-211, aa246-261 or aa326-354, which peptide has an immunity-inducing activity. These peptides are useful for therapy and/or prevention of cancers when administered to a living body, and are useful for inducing T cells which exert cytotoxic activity against cancer cells when used to stimulate the T cells in vitro.
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