THE ROCKEFELLER UNIVERSITY;SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
发明人:
RAVETCH, JEFFREY, V.,PINCETIC, ANDREW,WANG, PING,DANISHEFSKY, SAM
申请号:
EP12859843
公开号:
EP2793918A4
申请日:
2012.12.10
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Polypeptides that bind to DC-SIGN and/or its homologues and methods for using such peptides for the treatment of various disorders are described. DC-SIGN and its homologues are receptors that bind IgG antibodies or Fc fragments and mediate intravenous immunoglobulin (IVIG)-related reversal of inflammation associated with various immune disorders.