Humanization of rabbit antibodies using a universal antibody framework

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专利权人:

发明人:

申请号：

EP14162664.8

公开号：

EP2752428A1

申请日:

2009.06.25

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention relates to an universal antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a universal antibody acceptor framework. Antibodies generated by the methods of the invention are useful in a variety of diagnostic and therapeutic applications.

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