The present 3D-Flow OPRA is a revolutionary electronic instrument for multiple applications: advancing science, saving lives, finding and tracking fast moving objects, etc. It allows to build a flexible, scalable, technology-independent, cost effective powerful tool to uncover the unknown and to confirm or exclude the existence of a subatomic particle predicted by theoretical physicists. When used for Medical Imaging applications the 3D-Flow OPRA allows to accurately measure minimum abnormal biological processes of diseases at an early curable stage such as cancer in a 3D-CBS (3-D Complete Body Screening), improving diagnosis and prognosis to maximize reduction of premature deaths and minimize cost per each life saved. Both instruments, the 3D-Flow OPRA and the 3DCBS can benefit from the additional ER/DSU invention also described in this non-provisional patent application, which allows to record real data from detectors.