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Heterocyclic compounds as inhibitors of 17beta-HSD3
专利权人:
Nigel Vicker
发明人:
Nigel Vicker,Joanna Mary Day,Helen Victoria Bailey,Wesley Heaton,Ana Maria Ramos Gonzalez,Christopher Mark Sharland,Michael John Reed,Atul Purohit,Barry Victor Lloyd Potter
申请号:
US11968436
公开号:
US08119627B2
申请日:
2008.01.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
There is provided a compound having Formula (I)wherein each of rings A and B is selected from five or six membered carbon rings optionally containing one or more hetero atoms selected from N, S, and O and optionally having fused thereto a further ring X is an optional group selected from O, S, —S═O, —S(═O)2, —C═O, —S(═O)2NR8, —C═ONR9, and —NR10, wherein n and p are independently selected from 0 and 1 Y is (R11)1-3 wherein each R11 is independently selected from —NR12, —CR13R14, —S(═O)2 and —C═O Z is selected from (i) six or seven membered ring containing carbon and at least one nitrogen, which may be optionally substituted wherein the substituents may together form further ring fused thereto and (ii) a —R15—NR16— group.
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