A device for measuring electrophysiological data includes: a series of electrodes; a control circuit including a DC voltage source connected to the electrodes in order to apply, to a pair of electrodes, DC voltage pulses, and in order to connect another high-impedance electrode; and a measurement circuit for measuring the potential of the electrodes and data representative of the current passing through at least one active electrode. The device further includes at least one base incorporating the control circuit and the measurement circuit, and a housing suitable for receiving an electrode assembly which includes at least one electrode of the series in a removable manner, so as to be able to connect or disconnect the electrodes to/from the control circuit and to/from the measurement circuit.