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COMPOSITION CONTAINING INHIBITING CRYSTALLIZATION OF SUBSTANCE
专利权人:
ЮНИВЕРСИТАТ ДЕ ЛЕЗ ИЛЬ БАЛЕАР (ES)
发明人:
ГРАСЕС ФРЕЙХЕДАС Феликс (ES),ПЕРЕЛЛО БЕСТАРД Хуан (ES),ТУР ЭСПИНОЗА Фернандо (ES),КОСТА БАУЗА Антониа (ES),ПРИЕТО АЛМИРАЛЛ Рафаэль М. (ES),ГОМИЛА МУНИЗ Изабель (ES)
申请号:
RU2011115356/15
公开号:
RU2011115356A
申请日:
2009.05.14
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A composition comprising crystallization inhibiting substances selected from the group consisting of inositol phosphate, bisphosphonate, pharmaceutically acceptable salts, or any combination thereof, used to produce dialysis fluid. ! 2. The composition according to claim 1, in which the crystallization inhibiting substance is an inositol phosphate containing from 1 to 6 phosphate groups. ! 3. The composition according to claim 2, in which the inositol phosphate is an inositol hexaphosphate. ! 4. The composition according to claim 3, in which the inositol phosphate is myo-inositol hexaphosphate. ! 5. The composition according to claim 1, in which the bisphosphonate is selected from the group consisting of ethidronic acid, alendronic acid, risedronic acid, zoledronic acid, tiludronic, pamidronic acid, clodronic acid, ibandronic acid, salts, or any combination thereof. ! 6. The composition according to any one of claims 1 to 5, which further comprises pyrophosphate. ! 7. The composition according to any one of claims 1 to 5, in which the crystallization inhibiting substances are in a concentration of from 0.01 μM to 0.1 M.! 8. The composition according to claim 7, in which the crystallization inhibiting substances are in a concentration of from 0.1 μm to 10 mm. ! 9. The composition of claim 8, in which the crystallization inhibiting substances are in a concentration of from 0.1 μm to 5 mm. ! 10. A dialysis fluid containing crystallization inhibiting substances selected from the group consisting of inositol phosphate, bisphosphonate, pharmaceutically acceptable salts, or any combination thereof. ! 11. The use of dialysis fluid of claim 10 for hemodialysis or peritoneal dialysis. ! 12. Composition containing inositol phosphate and / or any of its salts in a form adapted for intravenous administration1. Композиция, содержащая ингибирующие кристаллизацию вещества, выбранные из группы, содержащей инозитолфосфат, бисфосфонат, фармацевтически приемлемые соли или любые их с
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