HELMHOLTZ ZENTRUM MÜNCHEN-DEUTSCHES FORSCHUNGS- ZENTRUM FÜR GESUNDHEIT UND;SIRION BIOTECH GMBH
发明人:
Natasa ANASTASOV,Ines Höfig,Christian Thirion
申请号：
US15713422
公开号：
US20180016600A1
申请日:
2017.09.22
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to a method for transducing a target cell, the method comprising the step of contacting a target cell with a retroviral vector and a poloxamer having a molecular weight of 12.8 kDa to about 15 kDa. Further, the invention relates to the use of a poloxamer as defined herein, optionally in combination with a polycationic substance as defined herein, for transducing a target cell with a retroviral vector and a kit comprising a retroviral vector, a poloxamer as defined herein and, optionally, instructions for use.
