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COMPOSE BICYCLIQUE CONTENANT DU SOUFRE
专利权人:
ASTELLAS PHARMA INC.
发明人:
SHIRAISHI, NOBUYUKI,HOSHII, HIROAKI,HAMAGUCHI, WATARU,HONJO, ERIKO,TAKUWA, TOMOFUMI,KONDO, YUJI,GOTO, TAKAYUKI
申请号:
CA2927518
公开号:
CA2927518A1
申请日:
2014.10.17
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
[Problem] To provide a compound useful as a pharmaceutical composition for prevention and/or treatment of diseases such as schizophrenia. [Solution] The inventors developed the present invention upon investigating a pharmaceutical composition having effects as a GABAB positive allosteric modulator (effects as a PAM), for preventing/treating diseases such as schizophrenia, and confirming that a sulfur-containing bicyclic compound has effects as a GABAB PAM. This sulfur-containing bicyclic compound has effects as a GABAB PAM and can be used as a preventive and/or therapeutic agent for diseases such as schizophrenia. (In the formula, X represents CH, R1 represents a lower alkyl, R2 represents a lower alkyl , R3 represents H, R4 represents H, ring A is a cyclohexane ring, RY represents a group represented by formula (III), Y represents NH, etc., and RL represents a lower alkyl.)
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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