A reservoir for use with a blood collection system includes a housing defining a cavity and a single stage filter. The housing has an inlet for receiving fluid from a source and an outlet. The inlet is in fluid communication with the cavity. The single stage filter includes a filter membrane configured to filter the fluid entering the housing from the inlet, and a frame defining the structure of the single stage filter. The frame also supports the filter membrane within the housing, and has a wiper edge that seals against an inner wall of the housing.