USE OF PIRFENIDONE AND DERIVATIVES FOR MODULATION OF B LYMPHOCYTE ACTIVITY AND ORGAN PROTECTION FROM ACUTE TISSUE DAMAGE

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专利权人:

Washington University

发明人:

Luigi Adamo,Douglas L. Mann,Roland Dolle

申请号：

US16638424

公开号：

US20200165203A1

申请日:

2018.07.31

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present disclosure relates to compositions and methods of modulating B lymphocyte activity, and organ protection after acute injury. In particular, PEG-Pirfenidone has increased half-life, improved bioavailability and is equipotent in modulating B cell activity and is particularly useful as protective agents from acute organ damage and disease caused by dysregulation of B cell activity.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/