Macrocyclic compounds comprising a portion in the Cycle pyrazolo [1,5-a] pyrimidine,Trk Kinase Inhibitors； Pharmaceutical composition； Preparation Process； and a method for treating a disorder selected from pain, cancer, inflammation,Neurodegenerative disease or infection by Trypanosoma cruzi.
QIAN ZHAO,KEVIN RONALD CONDROSKI,STEVEN WADE ANDREWS,JULIA HAAS,YUTONG JIANG,GABRIELLE R. KOLAKOWSKI,JEONGBEOB SEO,HONG-WOON YANG,HONG-WOON YANG.
申请号：
CL2012003227
公开号：
CL2012003227A1
申请日:
2012.11.20
申请国别(地区):
CL
年份:
2013
代理人:
摘要：
Macrocyclic Compounds, Pharmaceutical composition Trk Kinase Inhibitors；； Preparation Process； and a method for treating a disorder selected from pain, cancer, inflammation,Neurodegenerative disease or infection by Trypanosoma cruzi.<；p>；COMPUESTOS DE LA FORMULA I:<；br />；Y SALES FARMACÉ；UTICAMENTE ACEPTABLES DE É；STOS, EN DONDE EL ANILLO A, EL ANILLO B, W, M, D, R2, R2A, R3, R3A, Y Z SON COMO SE DEFINEN EN LA PRESENTE, QUE SON INHIBIDORES DE QUINASAS TRK Y SON Ú；TILES EN EL TRATAMIENTO DEL DOLOR, CÁ；NCER, INFLAMACIÓ；N, ENFERMEDADES NEURODEGENERATIVAS Y CIERTAS ENFERMEDADES INFECCIOSAS.<；br />； ；<；/p>；
