Compounds derived from (1.8) naftiridinas 2,4 diaryl substituted Kinase Inhibitors； Preparation Process； Pharmaceutical Composition and its use for the Treatment or prevention of cancer, tumor, malignant Tumors, among others； Pharmaceutical Kit.
DORSCH DIETER,JONCZYK ALFRED,HOELZEMANN GUENTER,AMENDT CHRISTIANE,ZENKE FRANK
申请号：
CL2012003680
公开号：
CL2012003680A1
申请日:
2012.12.26
申请国别(地区):
CL
年份:
2013
代理人:
摘要：
The present invention relates to novel [1,8]naphthyridine derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors.COMPUESTOS DERIVADOS DE [1,8]NAFTIRIDINAS-2,4-DIARIL SUSTITUIDAS CON ACTIVIDAD INHIBIDORA DE QUINASA； COMPOSICIÓN FARMACÉUTICA QUE LOS COMPRENDE； PROCEDIMIENTO DE PREPARACIÓN Y SU USO EN EL TRATAMIENTO DEL CÁNCER.
