SOARES DA SILVA, PATRICIO MANUEL VIEIRA ARAUJO,LEARMONTH, DAVID ALEXANDER,BELIAEV, ALEXANDER
申请号:
CA2686387
公开号:
CA2686387C
申请日:
2008.05.06
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Compounds of formula I and a method for their preparation are described, where R1, R2 and R3 are the same or different and signify hydrogens, halogens, alkyl, nitro, amino, alkylcarbonylamino, alkylamino or dialkylamino group R4 signifies -alkyl-aryl or alkyl heteroarylX signifies CH2, oxygen atom or sulphur atom n is 2 or 3 including the individual (R)- and (S)-enantiomers or mixtures of enantiomers thereof and including pharmaceutically acceptable salts and esters thereof. The compounds have potentially valuable pharmaceutical properties for the treatment of cardiovascular disorders such as hypertension and chronic heart failure.