NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, USE OF THE CATECHOL DERIVATIVE AND USE OF THE PHARMACEUTICAL COMPOSITION

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专利权人:

KISSEI PHARMACEUTICAL CO.; LTD.

发明人:

ISHIKAWA, TAKEHIRO,KOBAYASHI, SATOKO,INOUE, HITOSHI,UENO, YASUNORI,YOSHIDA, MASAKO,TANAKA, NOBUYUKI

申请号：

EP09773399

公开号：

EP2305633A4

申请日:

2009.06.26

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein R 1 and R 2 are each hydrogen, lower acyl, lower alkoxycarbonyl or the like R 3 is lower alkyl, halo-lower alkyl, cycloalkyl, heterocycloalkyl, optionally substituted aryl, optionally substituted heteroaryl or the like R 4 is cyano, lower alkoxycarbonyl, carboxy or the like, which exhibit potent COMT inhibitory activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.

来源网站：

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来源网址：

http://www.ckcest.cn/home/